RESUMO
La neumonía lipoidea aguda es una enfermedad poco frecuente producida por la aspiración masiva de material graso. Presenta unas características clínicas, radiológicas y histopatológicas muy llamativas y una evolución generalmente favorable.Se presenta un caso de neumonía lipoidea aguda en un varón de 26 años comedor de fuego
Acute lipoid pneumonia is an uncommon disease produced by massive aspiration of fatty substances. It has very striking clinical, radiological and histopathological characteristics and a generally favorable evolution.A case of acute lipoid pneumonia in a 26-year old male, "fire-eater" is presented
Assuntos
Humanos , Masculino , Adulto , Pneumonia Lipoide/diagnóstico , Pneumonia Aspirativa/diagnóstico , Óleo Mineral/efeitos adversos , Pneumonia Lipoide/etiologia , Pneumonia Aspirativa/etiologia , IncêndiosAssuntos
Imunossupressores/efeitos adversos , Pneumopatias/induzido quimicamente , Pulmão/efeitos dos fármacos , Talidomida/efeitos adversos , Tosse/induzido quimicamente , Dispneia/induzido quimicamente , Dispneia/diagnóstico , Humanos , Imunossupressores/administração & dosagem , Mieloma Múltiplo/tratamento farmacológico , Radiografia Torácica , Talidomida/administração & dosagemRESUMO
No disponible
Assuntos
Humanos , Procedimentos Cirúrgicos Minimamente Invasivos , Cirurgia Torácica Vídeoassistida , Radiografia Torácica , Talidomida , Satisfação do Paciente , Mieloma Múltiplo , Dispneia , Tosse , Imunossupressores , Pulmão , Tórax em Funil , PneumopatiasRESUMO
Capsaicin is the chemical responsible for the pungent, hot properties of Capsicum, a vegetable widely consumed in the diet of many countries in the world. In this work, the genotoxic capacity of capsaicin was studied in mouse during a 32-day treatment. We used the dosages of 1.46 and 1.94 mg/kg given by the i.p. route. Each week, the frequency of micronucleated normochromatic erythrocytes (MN-NE) and the ratio polychromatic/normochromatic erythrocytes (PE/NE) were scored. At the end of the experiment we also scored the frequency of sister chromatid exchanges (SCE). The results in the MN-NE analysis showed a genotoxic response with 1.94 mg/kg starting from day 16, while the 1.46 mg/kg dose produced a significant increase of MN-NE only at the 32nd day. The ratio PE/NE was only affected at the 32nd day with the high dose. Concerning the SCE frequency, the genotoxic effect was only observed with the highest dose. These results indicated that capsaicin is a genotoxicant, and due to the probable relation between an excessive consumption of Capsacum and an increase in gastric cancer, it is suggested that its consumption could be moderated until a definitive risk for humans is established.
